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Opioid overdose occurs when a person has excessive unopposed stimulation of the opiate pathway. This can lead to decreased respiratory effort and possibly death.  The frequency of opioid overdose is rapidly increasing. Drug overdose is the leading cause of accidental death in the United States, with opioids being the most common drug. The CDC currently estimates more than 1000 emergency department visits daily related to the misuse of opioids and about 91 opioid overdose deaths every day.

Source: Opioid, Overdose.

Authors: Schiller EY1, Mechanic OJ2.

SourceStatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018-.2018 Oct 27.