Product Overview

AOP Orphan's focus is on Rare Diseases. The portfolio comprises products in the following therapeutic areas: HematoOncology, Cardiology & Pulmonology, Neurology and Metabolic Disorders. AOP Orphan’s strategic goal is to constantly deliver new treatment options with respect to Rare Diseases.

Neurology & Metabolic Disorders

Adasuve®

Adasuve® is indicated for the rapid control of mild-to-moderate agitation (increased, unproductive physical activity coupled with internal tension) in adult patients with schizophrenia or biopolar disorder. Patients should receive regular treatment immediately after control of acute agitation symptoms. 

Drug Facts
Active Ingredient
Loxapine
HematoOncology

Anagrelide AOP

Anagrelide AOP is indicated for the reduction of elevated platelet counts and associated clinical symptoms in at high risk essential thrombocythemia patients.

Drug Facts
Active Ingredient
Anagrelide
Neurology & Metabolic Disorders

Artesyd®

Artesyd® is used at Hyperkinetic motor disorders with Huntington’s chorea and the treatment of moderate to severe tardive dyskinesia.

Drug Facts
Active Ingredient
Tetrabenazine
HematoOncology

Canemes®

Canemes® contains the active ingredient nabilone, a synthetically produced substance belonging to a group of compounds called cannabinoids (derived from cannabis plant). Canemes® prevents nausea and vomiting in patients undergoing chemotherapy for malignant tumours and is used if other drugs do not have the desired effect.

Drug Facts
Active Ingredient
Nabilone
Neurology & Metabolic Disorders

Dystardis®

Dystardis® is used for the treatment of diseases causing jerky, irregular, uncontrollable movements, hyperkinetic motor disorders with Huntington's chorea.

Drug Facts
Active Ingredient
Tetrabenazine
Cardiology & Pulmonology

Empressin®

Empressin® is used for the treatment of catecholamine refractory hypotension following septic shock in patients older than 18 years. A catecholamine refractory hypotension is present if the mean arterial blood pressur cannot be stabilized to 65 – 75 mmHg despite adequate volume substitution and application of catecholamines.

Drug Facts
Active Ingredient
Agripressin
Cardiology & Pulmonology

Esmocard®

Esmocard® is indicated for supraventricular tachycardia and for the rapid control of the ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short-acting agent is desirable.

Drug Facts
Active Ingredient
Esmolol
Cardiology & Pulmonology

Esmolol

Esmolol is indicated for supraventricular tachycardia and for the rapid control of the ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short-acting agent is desirable.

Drug Facts
Active Ingredient
Esmolol Hydrochloride
Neurology & Metabolic Disorders

Feraccru®

Feraccru® is indicated for adults for the treatment of iron deficiency.

Drug Facts
Active Ingredient
Ferric-maltol
Neurology & Metabolic Disorders

Motetis

Motetis is used as symptomatic therapy in the treatment of hyperkinetic motor disorders in Huntington’s disease. Tetrabenazine is also used in etiologist such as tardive dyskinesia, tics and dystonia.

Drug Facts
Active Ingredient
Tetrabenazine
Cardiology & Pulmonology

Naloxone

Naloxone hydrochloride is for complete or partial reversal of CNS and especially respiratory depression, caused by natural or synthetic opioids.

Drug Facts
Active Ingredient
Naloxone Hydrochloride Dihydrate
Neurology & Metabolic Disorders

Ocaliva®

Ocaliva® is indicated for the treatment of primary biliary cholangitis (also known to as primary biliary cirrhosis) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA or as monotherapy in adults unable to tolerate UDCA.

Drug Facts
Active Ingredient
Obeticholic acid
Neurology & Metabolic Disorders

Ospolot®

Ospolot® is an antiepileptic drug and is used to treat Rolandic epilepsy.

Drug Facts
Active Ingredient
Sultiame
Cardiology & Pulmonology

Remodulin®

Remodulin® is used to treat idiopathic or hereditary pulmonary arterial hypertension (PAH) in patients with medium to severe symptoms.

Drug Facts
Active Ingredient
Treprostinil
Neurology & Metabolic Disorders

Tardiben®

Tardiben® tablets are indicated for both hyperkinetic motor disorders associated with Huntington’s chorea and the treatment of moderate to severe tardive dyskinesia, which is an adverse effect associated with antipsychotic medicines.

Drug Facts
Active Ingredient
Tetrabenazine
Neurology & Metabolic Disorders

Tetmodis®

Tetmodis® is used as symptomatic therapy in the treatment of hyperkinetic motor disorders in Huntington’s disease. Tetrabenazine is also used in etiologies such as tardive dyskinesia, tics and dystonia.

Drug Facts
Active Ingredient
Tetrabenazine
Neurology & Metabolic Disorders

Tetrabenazine

Tetrabenazine is used as symptomatic therapy in the treatment of hyperkinetic motor disorders in Huntington’s disease. Tetrabenazine is also used in aetiology such as tardive dyskinesia, tics and dystonia.

Drug Facts
Active Ingredient
Tetrabenazine
HematoOncology

Thromboreductin®

Thromboreductin® is indicated for the reduction of elevated platelet counts and associated clinical symptoms in at high risk essential thrombocythemia patients

Drug Facts
Active Ingredient
Anagrelide
Neurology & Metabolic Disorders

Wakix®

Wakix® is indicated in adults for the treatment of narcolepsy with or without cataplexy.

Drug Facts
Active Ingredient
Pitolisant
Neurology & Metabolic Disorders

Yal®

Yal® is used for the colon & rectal cleansing preparation before operations.

Drug Facts
Active Ingredient
Sorbitolum