Product Overview

AOP Orphan's focus is on rare and special diseases. The portfolio comprises products in the following therapeutic areas: HematoOncology, Cardiology & Pulmonology, Neurology and Metabolic Disorders and Intensive Care. AOP Orphan’s strategic goal is to constantly deliver new treatment options with respect to rare and special diseases. 

Intensive Care

Nexodal

"Complete or partial reversal of CNS depressive effects, especially respiratory depression, caused by natural or synthetic opioids and partial agonist/antagonist opioids. It is also used to diagnose a suspected acute opioid overdose or intoxication or to reduce the effect of opioids, which were used for anesthesia in operations."

Drug Facts
Active Ingredient
Naloxone
Intensive Care

Nexodal

Nexodal is for complete or partial reversal of CNS and especially respiratory depression, caused by natural or synthetic opioids.

Drug Facts
Active Ingredient
Naloxone Hydrochloride Dihydrate
Neurology & Metabolic Disorders

Ocaliva®

Ocaliva® is indicated for the treatment of primary biliary cholangitis (also known to as primary biliary cirrhosis) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA or as monotherapy in adults unable to tolerate UDCA.

Drug Facts
Active Ingredient
Obeticholic acid
Cardiology & Pulmonology

Raploc®

Tadalafil AOP is used to treat adults with pulmonary arterial hypertension (PAH) to improve exercise capacity

Drug Facts
Active Ingredient
Landiolol Hydrochloride
Cardiology & Pulmonology

Tadalafil AOP

Tadalafil AOP is used to treat adults with pulmonary arterial hypertension (PAH) to improve exercise capacity

Drug Facts
Active Ingredient
Tadalafil
Neurology & Metabolic Disorders

Tetmodis®

Tetmodis® is used as symptomatic therapy in the treatment of hyperkinetic motor disorders in Huntington’s disease. Tetrabenazine is also used in etiologies such as tardive dyskinesia, tics and dystonia.

Drug Facts
Active Ingredient
Tetrabenazine
Neurology & Metabolic Disorders

Wakix®

Wakix® is indicated in adults for the treatment of narcolepsy with or without cataplexy.

Drug Facts
Active Ingredient
Pitolisant