Product Overview

AOP Orphan's focus is on rare and special diseases. The portfolio comprises products in the following therapeutic areas: HematoOncology, Cardiology & Pulmonology, Neurology and Metabolic Disorders and Intensive Care. AOP Orphan’s strategic goal is to constantly deliver new treatment options with respect to rare and special diseases. 

Neurology & Metabolic Disorders

Adepend

Adepend is used as part of a comprehensive programme of treatment against alcoholism to reduce the risk of relapse, as support treatment in abstinence and to reduce the craving for alcohol.

Drug Facts
Active Ingredient
Adepend
Neurology & Metabolic Disorders

Adepend® Dependex®

Adepend is used as part of a comprehensive treatment programme against alcoholism to reduce the risk of relapse, as support treatment in abstinence and to reduce the craving for alcohol.

Drug Facts
Active Ingredient
Naltrexone
HematoOncology

Anagrelide AOP

Anagrelide AOP is used to reduce the number of platelets in patients with essential thrombocythaemia.

Drug Facts
Active Ingredient
Anagrelide
Cardiology & Pulmonology

Argipressin AOP

Argipressin AOP is used to treat diabetes insipidus and bleeding from enlarged veins in the oesophagus.

Drug Facts
Active Ingredient
Argipressin
HematoOncology

BESREMi®

BESREMi® is indicated as monotherapy in adults for the treatment of Polycythaemia Vera without symptomatic splenomegaly.

Drug Facts
Active Ingredient
Ropeginterferon alfa-2b
Intensive Care

Empressin ®

"Argipressin based vasopressor indicated for the treatment of catecholamine refractory hypotension following septic shock in patients older than 18 years. A catecholamine refractory/resistant hypotension is present if the mean arterial blood pressure cannot be stabilized to >65 mmHg despite adequate volume substitution and application of catecholamines."

Drug Facts
Active Ingredient
Argipressin
Intensive Care

Empressin®

Empressin® is used for the treatment of catecholamine refractory hypotension following septic shock in patients older than 18 years. A catecholamine refractory hypotension is present if the mean arterial blood pressur cannot be stabilized to 65 – 75 mmHg despite adequate volume substitution and application of catecholamines.

Drug Facts
Active Ingredient
Agripressin
Intensive Care

Esmocard®

Esmocard® is indicated for supraventricular tachycardia and for the rapid control of the ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short-acting agent is desirable.

Drug Facts
Active Ingredient
Esmolol
Intensive Care

Esmocard® Lyo Esmolol Amomed

"Esmolol hydrochloride is indicated for supraventricular tachycardia (except for pre-excitation syndromes) and for the rapid control of the ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short-acting agent is desirable. Esmolol hydrochloride is also indicated for tachycardia and hypertension occurring in the perioperative phase and non-compensatory sinus tachycardia where, in the physician’s judgement the rapid heart rate requires specific intervention."

Drug Facts
Active Ingredient
Esmolol
Intensive Care

Esmolol®

Esmolol® is indicated for supraventricular tachycardia and for the rapid control of the ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short-acting agent is desirable.

Drug Facts
Active Ingredient
Esmolol Hydrochloride
Intensive Care

Naloxone

Naloxone hydrochloride is for complete or partial reversal of CNS and especially respiratory depression, caused by natural or synthetic opioids.

Drug Facts
Active Ingredient
Naloxone Hydrochloride Dihydrate
Neurology & Metabolic Disorders

Naltrexone hydrochloride

Naltrexone AOP is for use as an additional therapy within a comprehensive treatment program including psychological guidance for detoxified patients who have been opioid-dependent.

Drug Facts
Active Ingredient
Naltrexone hydrochloride
Intensive Care

Nexodal

"Complete or partial reversal of CNS depressive effects, especially respiratory depression, caused by natural or synthetic opioids and partial agonist/antagonist opioids. It is also used to diagnose a suspected acute opioid overdose or intoxication or to reduce the effect of opioids, which were used for anesthesia in operations."

Drug Facts
Active Ingredient
Naloxone
Neurology & Metabolic Disorders

Tetrabenazine

Tetrabenazine is used for the treatment of diseases causing jerky, irregular, uncontrollable movements (hyperkinetic motor disorders with Huntington’s chorea).

Drug Facts
Active Ingredient
Tetrabenazine